Nucleosomes store mechanical energy in the DNA wound around them. Nucleosome ejection releases the energy, powering a change in DNA conformation. The altered shape is recognized by proteins that use the energy to nucleate the local assembly of cellular machines.
Nucleosome Batteries
Nucleosomes represent one of smallest mechanical springs known and can power many nuclear events”— Alan HerbertCHARLESTOWN, MASSACHUSETTS, UNITED STATES, November 1, 2022 /EINPresswire.com/ — DNA is packed into cells by spooling the double helix around a spheroidal protein structure called a nucleosome. In a paper published online today in BioEssays entitled “Nucleosomes and flipons exchange energy to alter chromatin, conformation, the readout of genomic information, and cell fate”, Alan Herbert suggests that nucleosomes serve a quite…
The Nuclear Batteries in Every Cell
