Saturday, March 7, 2026

Human eggs remain healthy for decades by putting ‘batteries on standby mode’

Live cell imaging of human follicle, showing granulosa cells on the outer layer, which support the oocyte, contained within. The activity of reactive oxygen species is shown in red. The researchers observed ROS activity in the granulosa cells but it is virtually absent in the oocyte. Credit: Aida Rodriguez/Nature

Immature human egg cells skip a fundamental metabolic reaction thought to be essential for generating energy, according to the findings of a study by researchers at the Center for Genomic Regulation (CRG) published today in the journal Nature.

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