Many people worldwide suffer from a chronic type of inflammatory bowel disease (IBD) called ulcerative colitis (UC), which is characterized by erosions and ulcers within the mucous membrane of the colon (large intestine). It was understood that UC involves chronic and aggressive inflammation, but more specific details of its pathogenesis were not fully known.
Currently, there is no drug that can completely cure UC. Therefore, clinicians and scientists are aiming to develop a treatment that can target the actual molecular cause. In a recent article published in Scientific Reports, a team led by researchers at Osaka University described the design of an ingestible agent that was able to target the high levels of oxidation associated with UC in a lab mouse model.
Previous studies have shown that there are significant amounts of reactive oxygen species (ROS) in the intestinal mucosa of…
Hydrogen generated by Si-based agent attenuates inflammation in ulcerative colitis mouse model — ScienceDaily
